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MOTS-c (Mitochondrial ORF of the twelve-S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial genome. It functions as a metabolic regulator that translocates to the nucleus under metabolic stress to influence gene expression — earning it the description of an "exercise-mimetic" peptide.
Its principal mechanism is activation of the AMPK pathway, the cell's master energy sensor. Through AMPK, MOTS-c enhances glucose uptake, promotes fatty-acid oxidation, improves insulin sensitivity, and increases metabolic flexibility — the ability to switch efficiently between fuel sources.
Preclinical research links MOTS-c to improved exercise capacity, protection against diet-induced insulin resistance and obesity, and markers associated with healthy ageing and mitochondrial function.
Buy more vials, pay for fewer. Deals apply automatically per compound in your cart — the more you stock up, the less you pay per vial.
| Pack | You Pay | Per Vial | You Save |
|---|---|---|---|
| 1 vial | €49.99 | €49.99 | — |
| 5 vials (pay for 4) | €199.96 | €39.99 | 20% off |
| 10 vials (pay for 7) | €349.93 | €34.99 | 30% off |
| Monthly subscription (per vial) | €42.49/mo | €42.49 | 15% off |
Peptides are short chains of amino acids that act as biological messengers — signalling your cells to heal, regenerate, burn fat, or rebalance hormones. Your body produces them naturally, but output declines significantly with age, chronic stress, and injury.
In research settings, synthetic peptides replicate and amplify these signals with remarkable specificity. They bind to targeted receptors on cell surfaces, triggering precise downstream responses without the broad side-effect profiles of conventional compounds — one of the most exciting frontiers in modern longevity and performance research.